Methods and apparatus to deploy workload domains in virtual server racks are disclosed. An example apparatus includes a policy manager to determine an availability option and a performance option of the workload domain based on a domain type and determine capacity options based on a user selection of the availability option and a user selection of the performance option by a first user, a deployment manager to identify first ones of a plurality of computing resources to form a placement solution for the workload domain based on the user selection of the availability and performance options, and based on a user selection of one of the determined capacity options by the first user, the plurality of computing resources stored in a resource database accessible by the first user and a second user, and a resource manager to reserve the first ones of the plurality of computing resources to deploy the workload domain for the first user.