Embodiments of a system and method for generating integrated circuit layouts are described herein. A computer implemented method for generating integrated circuit layouts includes receiving a first layout for an integrated circuit, segmenting the first layout into a plurality of different patches, each patch of the plurality of patches describing a discrete portion of the first layout, identifying a non-compliant patch of the plurality of patches, the non-compliant patch violating a design rule governing the manufacture of the integrated circuit, generating a transformation of the non-compliant patch using a machine learning model, and generating a second layout using the transformation and the first layout, where the second layout is compliant with the design rule.