A method, apparatus, and device for determining aging degrees of pixels in a display panel, and a method, apparatus, and device for compensating display luminance of pixels. The method for determining the aging degrees of the pixels in the display panel includes: for each pixel of at least a part of pixels in the display panel that includes multiple pixels, determining electric current data and temperature data of the pixel; and based on the determined current data and temperature data, calculating aging degree data of the pixel according to an attenuation model.