A method for controlling transmission power in a wireless communication system, and an apparatus therefor are disclosed in the disclosure. Specifically, the method for controlling uplink transmission power in a wireless communication system, that is performed by a terminal, may comprise the steps of: receiving from a base station power control configuration information with respect to a plurality of power control domains by means of higher layer signalling; receiving from the base station downlink control information (DCI) including transmission power control (TPC) information with respect to at least one of the plurality of power control domains; and performing uplink transmission using transmission power that is determined based on the power control configuration information and the TPC information.