The concepts and technologies disclosed herein are directed to quantum security enhancement for IPsec protocol. According to one aspect disclosed herein, a quantum resource manager (“Q-RM”) can find a recommended quantum routing path for routing data from a first data center to a second data center via a pair of entangled quantum particles. The Q-RM can instruct a first quantum node (“QN”) associated with the first data center and a second QN associated with the second data center to establish a quantum channel that facilitates the recommended quantum routing path. The Q-RM can prepare an IPsec encrypted tunnel to carry a qubit associated with the pair of entangled quantum particles from the first data center to the second data center. The Q-RM can find the recommended quantum routing path responsive to an issue detected with the IPsec encrypted tunnel previously established between the first data center and the second data center.