Invention Grant
- Patent Title: Lipid nanoparticles for delivering modified RNA encoding a VEGF-A polypeptide
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Application No.: US16760406Application Date: 2018-10-31
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Publication No.: US11696892B2Publication Date: 2023-07-11
- Inventor: Kenny Mikael Hansson , Kerry Benenato , Maria Wågberg , Annika Pålsson , Regina Fritsche-Danielson
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2018/058541 2018.10.31
- International Announcement: WO2019/089818A 2019.05.09
- Date entered country: 2020-04-29
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61P43/00 ; A61K31/7088 ; A61K38/18 ; B82Y5/00 ; A61K9/00

Abstract:
The disclosure relates to nanoparticles comprising a lipid component and a modified RNA encoding a VEGF-A polypeptide. Aspects of the disclosure further relate to uses of nanoparticles comprising a lipid component and a modified RNA encoding a VEGF-A polypeptide, for improving wound healing in a subject.
Public/Granted literature
- US20200338004A1 LIPID NANOPARTICLES FOR DELIVERING MODIFIED RNA ENCODING A VEGF-A POLYPEPTIDE Public/Granted day:2020-10-29
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