- 专利标题： Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells
-
申请号： US16437844申请日： 2019-06-11
-
公开(公告)号： US11697819B2公开(公告)日： 2023-07-11
- 发明人: Oded Shoseyov , Helena Magrisso , Tzvi Zvirin , Amit Yaari , Zohar Katz
- 申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 申请人地址： IL Jerusalem
- 专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
- 当前专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
- 当前专利权人地址： IL Jerusalem
- 代理机构： Booth Udall Fuller, PLC
- 代理商 Scott H. Blackman
- 主分类号： C12N15/82
- IPC分类号： C12N15/82 ; C12N15/62 ; C12P21/00 ; C07K16/22 ; C07K16/24 ; C12N9/24
摘要：
A method of modifying a glycosylation pattern of a polypeptide-of-interest in a plant or plant cell is provided. The method comprising expressing in a plant or plant cell transformed to express at least one glycosidase in a subcellular compartment, a nucleic acid sequence encoding the polypeptide-of-interest, such that the at least one glycosidase and the polypeptide-of-interest are co-localized to the subcellular compartment of the plant or plant cell, thereby modifying the glycosylation pattern of the polypeptide-of-interest in the plant or plant cell.
公开/授权文献
信息查询
IPC分类:
