Systems, apparatuses, and methods for performing asynchronous memory clock changes on multiple displays are disclosed. From time to time, a memory clock frequency change is desired for a memory subsystem storing frame buffer(s) used to drive pixels to multiple displays. For example, when the real-time memory bandwidth demand differs from the memory bandwidth available with the existing memory clock frequency, a control unit tracks the vertical blanking interval (VBI) timing of a first display. Also, the control unit causes a second display to enter into panel self-refresh (PSR) mode. Once the PSR mode of the second display overlaps with a VBI of the first display, a memory clock frequency change, including memory training, is initiated. After the memory clock frequency change, the displays are driven by the frame buffer(s) in the memory subsystem at an updated frequency.