- 专利标题: 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
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申请号: US16486541申请日: 2018-02-15
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公开(公告)号: US11702408B2公开(公告)日: 2023-07-18
- 发明人: Aimee Crombie Speerschneider , Dennis Shinji Yamashita , Philip Michael Pitis , Michael John Hawkins , Guodong Liu , Tamara Ann Miskowski Daubert , Catherine C. K. Yuan , Robert Borbo Kargbo , Robert Jason Herr , Donna Romero
- 申请人: Trevena, Inc.
- 申请人地址: US PA Chesterbrook
- 专利权人: TREVENA, INC.
- 当前专利权人: TREVENA, INC.
- 当前专利权人地址: US PA Chesterbrook
- 代理机构: Goodwin Procter LLP
- 国际申请: PCT/US2018/018312 2018.02.15
- 国际公布: WO2018/152293A 2018.08.23
- 进入国家日期: 2019-08-16
- 主分类号: C07D403/12
- IPC分类号: C07D403/12 ; C07D403/14 ; A61P25/22 ; A61P25/24 ; A61P25/06 ; A61P29/00
摘要:
The present embodiments are directed, in part, to 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, such as those of Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinson's Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof.
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