Invention Grant
- Patent Title: Optimized anti-FLT1 oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders
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Application No.: US17846526Application Date: 2022-06-22
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Publication No.: US11702659B2Publication Date: 2023-07-18
- Inventor: Anastasia Khvorova , Vignesh Narayan Hariharan , Sarah Davis , Annabelle Biscans , Ananth Karumanchi
- Applicant: University of Massachusetts , Beth Israel Deaconess Medical Center, Inc.
- Applicant Address: US MA Boston
- Assignee: UNIVERSITY OF MASSACHUSETTS,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- Current Assignee: UNIVERSITY OF MASSACHUSETTS,BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
- Current Assignee Address: US MA Boston; US MA Boston
- Agency: Lathrop GPM LLP
- Agent James H. Velema, Esq.; Michael J. Spellberg, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; A61P7/00
Abstract:
This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided.
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