A method of controlling a pattern skin lighting device for a vehicle is provided. The method includes generating a plurality of random numbers and accumulating the number of continuous turn-on times for each lightening cell in an arrangement of the lightening cells configuring a pattern skin lighting device. Additionally, the method includes selecting a turn-on target lightening cell, lightening cells having an accumulative value of the number of continuous turn-on times that is a predetermined reference value or less, among the lightening cells corresponding to the generated random number, and turning on a light emitting element of the selected turn-on target lightening cell.