Various embodiments of apparatuses and methods for protecting data integrity in a content distribution network (“CDN”) are described. Code or data in one of the servers or instances of a CDN might sometimes become incorrect or corrupt. One corrupted server or instance can potentially impact a considerable portion of the CDN. To solve these and other problems, various embodiments of a CDN can designate one or more parameters, which are then identified in a request for content to another entity. In these embodiments, the CDN can generate an encoding of the expected values of the designated parameters. The CDN can then compare, in these embodiments, its encoding of the expected values to an encoding of the values received from the other entity in response to the request. The CDN can validate the content of the response, as well as the identity of the other entity, in some embodiments.