Invention Grant
- Patent Title: Compositions comprising an anti-LAG-3 antibody or an anti-LAG-3 antibody and an anti-PD-1 or anti-PD-L1 antibody
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Application No.: US16616583Application Date: 2018-05-30
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Publication No.: US11723975B2Publication Date: 2023-08-15
- Inventor: Lori S. Burton , William Ying , Nils Lonberg , Sudhir Chakravarthi , Pedro Smith
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/US2018/035142 2018.05.30
- International Announcement: WO2018/222722A 2018.12.06
- Date entered country: 2019-11-25
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K9/00 ; A61K45/06 ; A61K47/02 ; A61K47/12 ; A61K47/18 ; A61K47/22 ; A61K47/26 ; A61K47/34 ; C07K16/28 ; A61J1/14 ; A61K39/00

Abstract:
This provides pharmaceutical compositions that comprise (i) an anti-LAG-3 antibody or antigen binding fragment thereof or (ii) an anti-LAG-3 antibody or antigen binding fragment thereof and an anti-PD-1 antibody, anti-PD-L1 antibody, or antigen binding fragment thereof. Also provided are pharmaceutical compositions that comprise a buffering agent, stabilizing or bulking agent, and a surfactant. The disclosure also provides a vial, syringe, intravenous bag, or kit that comprises the compositions, and methods for using the compositions.
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