- 专利标题： Compositions and methods for liquid phase oligonucleotide synthesis
-
申请号： US17562714申请日： 2021-12-27
-
公开(公告)号： US11725073B2公开(公告)日： 2023-08-15
- 发明人: Aldrich N. K. Lau , Xiaoyang Guan , David Yu
- 申请人： Hongene Biotech Corporation
- 申请人地址： US CA Union City
- 专利权人： Hongene Biotech Corporation
- 当前专利权人： Hongene Biotech Corporation
- 当前专利权人地址： US CA Union City
- 代理机构： Knobbe, Martens, Olson & Bear LLP
- 主分类号： C07H19/00
- IPC分类号： C07H19/00 ; C07H21/02 ; A61K47/54 ; A61K47/58 ; C08F220/22
摘要：
Embodiments of the present application relate to polymers for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis, comprising dissolving a polyvalent hub having a plurality of functional groups in a solvent and contacting the polyvalent hub with one or more nucleoside analogs to form a first bioconjugate are also provided.
公开/授权文献
信息查询
