Invention Grant
- Patent Title: Methods for making and using sinoatrial node-like pacemaker cardiomyocytes and ventricular-like cardiomyocytes
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Application No.: US16737768Application Date: 2020-01-08
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Publication No.: US11730770B2Publication Date: 2023-08-22
- Inventor: Gordon Keller , Stephanie Protze
- Applicant: UNIVERSITY HEALTH NETWORK
- Applicant Address: CA Toronto
- Assignee: University Health Network
- Current Assignee: University Health Network
- Current Assignee Address: CA Toronto
- Agency: Wolf, Greenfield & Sacks, P.C.
- The original application number of the division: US15550572
- Main IPC: A61K35/34
- IPC: A61K35/34 ; C12N5/077 ; C12N5/10

Abstract:
Provided are methods for producing compositions comprising a population of cardiomyocytes enriched for or substantially devoid of sinoatrial node-like pacemaker cardiomyocytes (SANLCM) from human pluripotent stem cells (hPSCs), and methods of use thereof.
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