In various examples, as a user is speaking or presenting content during an online video conference, the data stream may be processed to generate a textual representation (e.g., transcript) of the audio and/or information relating to the video. The textual representation and/or video related information may then be processed to determine a context or one or more topic(s) of discussion. Based on the determined context/topic(s), a corresponding neural network(s) may be selected. Once a neural network has been selected, comments may be retrieved from a chat feature of the application and applied to the neural network. The neural network may then output data to indicate the relevance of the comments to the determined discussion topic. Based on the relevance of the comment, the comment may be allowed, prioritized, deleted, de-emphasized, or otherwise filtered in the chat feature.