Bandwidth part (BWP) inactivity and mode switching supporting various communication approaches (e.g., full duplex and/or half duplex operations) are described. A wireless device may be provided with multiple BWP configurations, such as may include a default half duplex BWP configuration and a default BWP configuration. Multiple timers, such as may include a BWP inactivity timer and a duplex mode timer, may be implemented for timer-based switching between BWP configurations, such as any combination of a default half duplex BWP configuration, an active half duplex BWP configuration, a default full duplex BWP configuration, and an active full duplex BWP configuration. Other aspects and features are also claimed and described.