- 专利标题: Traditional Chinese medicine composition for treating metabolic syndrome and preparations thereof
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申请号: US17274968申请日: 2019-09-17
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公开(公告)号: US11744870B2公开(公告)日: 2023-09-05
- 发明人: Ximing Liu , Hong Li
- 申请人: JIANGSU JIUXU PHARMACEUTICAL CO., LTD. , Hong Li
- 申请人地址: CN Jiangsu
- 专利权人: JIANGSU JIUXU PHARMACEUTICAL CO., LTD.,Hong Li
- 当前专利权人: JIANGSU JIUXU PHARMACEUTICAL CO., LTD.,Hong Li
- 当前专利权人地址: CN Jiangsu; CN Jiangsu
- 代理机构: Paratus Law Group, PLLC
- 优先权: CN 1811080557.5 2018.09.17
- 国际申请: PCT/CN2019/106196 2019.09.17
- 国际公布: WO2020/057503A 2020.03.26
- 进入国家日期: 2021-03-10
- 主分类号: A61K36/718
- IPC分类号: A61K36/718 ; A61P3/10 ; A61K31/366 ; A61K31/4375 ; A61K31/7048 ; A61K36/062 ; A61K36/428 ; A61K36/54 ; A61K36/752 ; A61K36/8888
摘要:
Disclosed are a traditional Chinese medicine composition and a traditional Chinese medicine extract composition for treating metabolic syndrome. The traditional Chinese medicine composition consists of the following raw materials in the following weight ratio: 5-80% of Coptidis Rhizoma, 5-70% of Aurantii Fructus Immaturus, 0-60% of Pinelliae Rhizoma, 0-40% of Trichosanthis Fructus, 0-12% of Cinnamomi Cortex, and 10-60% of red yeast rice. The traditional Chinese medicine extract composition consists of the following raw materials in the following weight ratio: 2-30% of Coptidis Rhizoma extract, and 70-98% of a mixed extract from five traditional Chinese medicines comprising Aurantii Fructus Immaturus, Pinelliae Rhizoma, red yeast rice, Trichosanthis Fructus, and Cinnamomi Cortex. The traditional Chinese medicine composition or the traditional Chinese medicine extract composition contains the following active ingredients (mg/g): 6-122 mg/g of total alkaloids, which comprises 4-89 mg/g of berberine, 30-315 mg/g of total flavonoids, which comprises 20-186 mg/g of neohesperidin: and 0.5-9 mg/g of lovastatin. Further provided are preparation methods and applications of the above compositions.
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