A display panel, a method of manufacturing the same, and a display device are provided. In the display panel, sub-pixel areas in a same row along a first direction are divided into a plurality of sub-pixel area groups independent from each other, and each sub-pixel area group includes at least two adjacent sub-pixel areas, a connection layer includes a connection pattern arranged in each sub-pixel area, and the connection pattern is coupled to the initialization signal line pattern in the sub-pixel area wherein the connection pattern is located, connection patterns located in a same sub-pixel area group are sequentially coupled along the first direction to form the connection portion; at least part of a first auxiliary signal line layer is located in an anode spacing area, and is insulated from an anode pattern, the connection pattern in each sub-pixel area group is coupled to the first auxiliary signal line layer.