Invention Grant
- Patent Title: Compounds and compositions for treating solid tumors by intratumoral administration
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Application No.: US16614280Application Date: 2018-05-17
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Publication No.: US11752162B2Publication Date: 2023-09-12
- Inventor: Michael Cooke , Shailaja Kasibhatla , Andrew T. Miller , Tom Yao-Hsiang Wu
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Biospark Intellectual Property Law
- International Application: PCT/IB2018/053481 2018.05.17
- International Announcement: WO2018/211453A 2018.11.22
- Date entered country: 2019-11-15
- Main IPC: A61P35/04
- IPC: A61P35/04 ; A61K31/675 ; A61K9/00 ; A61K9/10 ; A61K9/19 ; A61K47/02 ; A61K47/26 ; C07K16/28

Abstract:
The invention provided herein includes pharmaceutical compositions comprising a TLR7 agonist having the structure of Formula (A), aluminum-containing particles, and one or more pharmaceutically acceptable excipient. The invention further provides the use of such compositions in the treatment of solid tumors either alone or in combination with one or more additional pharmaceutical compositions.
Public/Granted literature
- US20210154214A1 COMPOUNDS AND COMPOSITIONS FOR TREATING SOLID TUMORS BY INTRATUMORAL ADMINISTRATION Public/Granted day:2021-05-27
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