Invention Grant
- Patent Title: Compounds and compositions for inducing chondrogenesis
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Application No.: US17368537Application Date: 2021-07-06
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Publication No.: US11753416B2Publication Date: 2023-09-12
- Inventor: Ha-Soon Choi , Jiqing Jiang , James Paul Lajiness , Bao Nguyen , Hank Michael James Petrassi
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Emily T. Wu
- Main IPC: C07D493/08
- IPC: C07D493/08 ; A61K9/00 ; A61K31/343

Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof;
or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating joint damage or injury in a mammal, for inducing hyaline cartilage production or for inducing differentiation of chondrogenic progenitor cells into mature chondrocytes.
or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds; and methods of using such compounds for treating joint damage or injury in a mammal, for inducing hyaline cartilage production or for inducing differentiation of chondrogenic progenitor cells into mature chondrocytes.
Public/Granted literature
- US20210347784A1 COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS Public/Granted day:2021-11-11
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