A granule comprising (a) at least three cores comprising a biological active and a plasticizable polymer, wherein the cores are made of a material having an elongation upon break of at least 30%, and wherein the diameter of the cores is at least 50 μm and at most two thirds of the diameter of the granule; (b) a solid matrix interspacing the cores of (a), wherein the solid matrix is made of a material having an elongation upon break of less than 30%; and (c) optionally a coating consisting of one or more layer(s) surrounding the granule. A detergent composition comprising a detergent builder, a surfactant, and a granule as described. Use of the granule as a component in a process for manufacturing a detergent composition.