- 专利标题： Method of treating a tumor in a patient based on an immune gene expression
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申请号： US16767366申请日： 2018-12-21
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公开(公告)号： US11756651B2公开(公告)日： 2023-09-12
- 发明人: Kevin B. Givechian , Kamil A. Wnuk , Chad Garner , Stephen Charles Benz , Hermes J. Garban , Shahrooz Rabizadeh , Kayvan Niazi , Patrick Soon-Shiong
- 申请人： NANTOMICS, LLC , NANTBIO, INC. , NANT HOLDINGS IP, LLC
- 申请人地址： US CA Culver City
- 专利权人： Nantomics LLC,NantBio, Inc.,Nant Holdings IP, LLC
- 当前专利权人： Nantomics LLC,NantBio, Inc.,Nant Holdings IP, LLC
- 当前专利权人地址： US CA Culver City; US CA Culver City; US CA Culver City
- 代理机构： Umberg Zipser LLP
- 代理商 Martin Fessenmaier
- 国际申请： PCT/US2018/067319 2018.12.21
- 国际公布： WO2019/135957A 2019.07.11
- 进入国家日期： 2020-05-27
- 主分类号： G16B25/10
- IPC分类号： G16B25/10 ; C12Q1/6886
摘要：
An immune gene expression signature is associated with favorable clinical features in Treg-enriched tumor samples and can be used to predict immunogenicity of a tumor, overall survival, and/or chemosensitivity.
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