A chip package structure is provided. The chip package structure includes a first chip, a second chip, and a third chip. The chip package structure includes a first molding layer surrounding the first chip and the second chip. The first molding layer is a single layer structure. A first boundary surface between the passivation layer and the second molding layer extends toward the first chip. The chip package structure includes a second molding layer surrounding the third chip and the first molding layer. A first bottom surface of the first molding layer and a second bottom surface of the second molding layer are substantially coplanar.