An electronic device with a flexible display screen includes: a housing with a first housing and a second housing enclosed to form a receiving structure; a sliding rail mechanism arranged in the receiving structure, connected to the second housing, and slidably arranged to the first housing; a flexible display screen with a first end connected to the sliding rail mechanism and a second end connected to the first housing; and a support assembly including a first support plate connected to the first housing and a second support plate slidably connected to the first support plate as well as connected to the sliding rail mechanism. The sliding rail mechanism drives the first end of the flexible display screen to be switched between an expanded state and a retracted state. When expanding, the second support plate slides relative to the first support plate to support the expanded part of the flexible display screen.