The present invention aims at providing a cam clutch that prevents cams from unwanted wedging and enables smooth operation including the switching between operation modes without involving an increase in size or number of components and with a simple structure. The cam clutch according to the present invention uses first cams and second cams having different engaging directions as sprags for transmitting and interrupting torque between an inner race and an outer race. A cam interlock mechanism tilts the second cams to a disengaging direction with a tilting motion of the first cams toward an engaging direction, to separate engaging surfaces of the second cams from raceways of the inner race and/or the outer race.