A system and a method are disclosed for estimating antenna misalignments in a line-of-sight wireless communication system and using the estimated antenna misalignments to form an optimal beam that may provide the best performance based on the channel conditions. A receiver determines a rotational estimate and a translational estimate of the receiver with respect to a transmitter, and sends feedback information to the transmitter that is used to determine an optimal beamforming matrix for LOS communications between the receiver and the transmitter. The feedback information includes estimated rotational angles and an estimated translational distance between the receiver and the transmitter, or includes an offset angle between a first plane of antennas of the receiver and a second plane of antennas of the transmitter, a normal vector of the first plane of antennas and the estimated translational distance. The antennas may be antenna arrays or single-element antennas.