This disclosure provides systems, devices, apparatus and methods, including computer programs encoded on storage media, for GPR optimization in a GPU based on a GPR release mechanism. More specifically, a GPU may determine at least one unutilized branch within an executable shader based on constants defined for the executable shader. Based on the at least one unutilized branch, the GPU may further determine a number of GPRs that can be deallocated from previously allocated GPRs. The GPU may deallocate, for a subsequent thread within a draw call, the number of GPRs from the previously allocated GPRs during execution of the executable shader based on the determined number of GPRs to be deallocated.