- 专利标题: Viral vector production
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申请号: US16612497申请日: 2018-05-11
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公开(公告)号: US11767539B2公开(公告)日: 2023-09-26
- 发明人: Jun Xie , Guangping Gao
- 申请人: University of Massachusetts
- 申请人地址: US MA Boston
- 专利权人: University of Massachusetts
- 当前专利权人: University of Massachusetts
- 当前专利权人地址: US MA Boston
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 国际申请: PCT/US2018/032291 2018.05.11
- 国际公布: WO2018/209216A 2018.11.15
- 进入国家日期: 2019-11-11
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C12N15/113 ; C12Q1/68
摘要:
In some aspects, the disclosure relates to methods for improving titer and yield of viral vector production. In some embodiments, the methods comprise transient silencing of transgene expression during packaging of a viral vector.
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