Invention Grant
- Patent Title: RNA polymerase variants
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Application No.: US17350662Application Date: 2021-06-17
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Publication No.: US11767548B2Publication Date: 2023-09-26
- Inventor: Amy E. Rabideau , Athanasios Dousis , Kanchana Ravichandran , Elissa Hobert
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- The original application number of the division: US16432541 2019.06.05
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N9/12 ; C12P19/34

Abstract:
The present disclosure provides, in some aspects, variant RNA polymerases, the use of which increases transcription efficiency while reducing the number of double-stranded RNA contaminates and run-on transcripts produced during an in vitro transcription reaction.
Public/Granted literature
- US20210395792A1 RNA POLYMERASE VARIANTS Public/Granted day:2021-12-23
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