A dynamic user interface (UI) input system and method for smart glasses based on availability states of a user is provided. In embodiments, a method includes determining, by a computing device of smart glasses, an initial availability state of a user's hands for a user interface (UI) navigation event based on incoming image data; selecting, by the computing device, a UI configuration and a control profile for the UI navigation event from stored UI configurations and control profiles of the user based on the initial availability state of the user's hands; and initiating, by the computing device, the UI navigation event based on the selected UI configuration and the control profile, wherein content is displayed in a virtual UI of the smart glasses according to the UI configuration, and UI navigation by the user is controlled based on the control profile.