Example aspects of the present disclosure are directed to computing systems and methods for hand tracking using a machine-learned system for palm detection and key-point localization of hand landmarks. In particular, example aspects of the present disclosure are directed to a multi-model hand tracking system that performs both palm detection and hand landmark detection. Given a sequence of image frames, for example, the hand tracking system can detect one or more palms depicted in each image frame. For each palm detected within an image frame, the machine-learned system can determine a plurality of hand landmark positions of a hand associated with the palm. The system can perform key-point localization to determine precise three-dimensional coordinates for the hand landmark positions. In this manner, the machine-learned system can accurately track a hand depicted in the sequence of images using the precise three-dimensional coordinates for the hand landmark positions.