Invention Grant
- Patent Title: Sacubitril calcium salts
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Application No.: US15737985Application Date: 2015-07-02
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Publication No.: US11786498B2Publication Date: 2023-10-17
- Inventor: David Hook , Bin Hu , Florian Karl Kleinbeck , Ulrich Meier , Sibylle Mueller , Jean-Paul Mutz , Jan Schlomach , Paul Allen Sutton , Liladhar Murlidhar Waykole , Bernhard Wietfeld
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Timothy P. O'Dea
- International Application: PCT/US2015/039010 2015.07.02
- International Announcement: WO2017/003483A 2017.01.05
- Date entered country: 2017-12-19
- Main IPC: A61K31/22
- IPC: A61K31/22 ; A61P9/10 ; A61P9/06 ; A61P25/02 ; C07C229/34 ; A61P9/12 ; A61P25/06 ; A61K31/4178 ; A61K31/423
Abstract:
The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.
Public/Granted literature
- US20180296519A1 SACUBITRIL CALCIUM SALTS Public/Granted day:2018-10-18
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