Systems and methods for deployment of electric-based fracturing tools in vertical wells are disclosed. A method of electric-based fracturing may include lowering an electrical stimulation tool into a wellbore using a drill pipe and isolating a lower portion of the wellbore that is downhole from an upper portion of the wellbore. The electrical stimulation tool may be disposed in the lower portion of the wellbore. A system for electric-based fracturing may include an isolation mechanism and an electrical stimulation tool. The isolation mechanism may be configured to expand from a retracted configuration spaced from an interior surface of a wellbore to an expanded configuration in contact with the inner surface of the wellbore. The electrical stimulation tool may be operatively coupled with the isolation mechanism and may be configured to be disposed distally relative to the isolation mechanism when positioned in the wellbore.