Invention Grant
- Patent Title: Pyrrolotriazinones and imidazotriazinones as ubiquitin-specific protease 7 inhibitors
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Application No.: US17230603Application Date: 2021-04-14
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Publication No.: US11795171B2Publication Date: 2023-10-24
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell
- Applicant: Valo Health, Inc.
- Applicant Address: US MA Boston
- Assignee: Valo Health, Inc.
- Current Assignee: Valo Health, Inc.
- Current Assignee Address: US MA Boston
- Agency: Choate, Hall & Stewart LLP
- Agent Kristen C. Buteau; Michael A. Shinall
- Main IPC: C07D487/04
- IPC: C07D487/04
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:
where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.
where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.
Public/Granted literature
- US20220033403A1 PYRROLOTRIAZINONES AND IMIDAZOTRIAZINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS Public/Granted day:2022-02-03
Information query
