This invention provides a co-disposal pollution control method of municipal solid waste and fly ash leached by membrane concentrate, obtained residue and application thereof. A co-disposal pollution control method of municipal solid waste and fly ash leached by membrane concentrate, comprising the following steps: heat treating the mixture of leached ash and municipal solid waste at 800-1100° C. to obtain residue; the leaching ash is fly ash after being leached with membrane concentrate. The invention solves the problems existed in the co-disposal treatment of membrane concentrate, incineration fly ash and municipal solid waste, and the leaching toxicity of the ash leached by the membrane concentrated solution is reduced, moreover, the leaching concentration of heavy metals in the residue obtained after the leaching treatment is treated with municipal solid waste at medium and high temperature, and the residue obtained after heat treatment can be used as building materials.