Invention Grant
- Patent Title: Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
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Application No.: US16663583Application Date: 2019-10-25
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Publication No.: US11802162B2Publication Date: 2023-10-31
- Inventor: Changyu Wang , Nils Lonberg , Alan J. Korman , Mark J. Selby , Mohan Srinivasan , Karla A. Henning , Michelle Minhua Han , Guodong Chen , Richard Huang , Indrani Chakraborty , Haichun Huang , Susan Wong , Huiming Li
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- The original application number of the division: US15369290 2016.12.05
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K47/68 ; A61K39/395 ; G01N33/68 ; G01N33/574 ; A61K39/00

Abstract:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
Information query