Invention Grant
- Patent Title: TLR 9 inhibitors
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Application No.: US17240792Application Date: 2021-04-26
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Publication No.: US11807622B2Publication Date: 2023-11-07
- Inventor: Aleksandrs Zavoronkovs , Vladimir Aladinskiy , Aleksandr Aliper
- Applicant: Insilico Medicine IP Limited
- Applicant Address: HK Hong Kong
- Assignee: Insilico Medicine IP Limited
- Current Assignee: Insilico Medicine IP Limited
- Current Assignee Address: HK Hong Kong
- Agency: Wilson Sonsini Goodrich & Rosati
- The original application number of the division: US16262631 2019.01.30
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14

Abstract:
A TLR9 inhibitor includes a compound of general formula (I):
wherein the meanings of the variables are explained in the specification,
or a stereoisomeric form or a mixture of stereoisomeric forms, or pharmaceutically acceptable salts thereof. A pharmaceutical composition can include compounds of the invention, which can be used in a method for inhibiting TLR9 activity in vitro or in vivo. The method can be performed by administering the compound to a subject to inhibit TLR9 activity, which can be used to treat a disease or disorder associated with TLR9.
wherein the meanings of the variables are explained in the specification,
or a stereoisomeric form or a mixture of stereoisomeric forms, or pharmaceutically acceptable salts thereof. A pharmaceutical composition can include compounds of the invention, which can be used in a method for inhibiting TLR9 activity in vitro or in vivo. The method can be performed by administering the compound to a subject to inhibit TLR9 activity, which can be used to treat a disease or disorder associated with TLR9.
Public/Granted literature
- US20210253553A1 TLR 9 INHIBITORS Public/Granted day:2021-08-19
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