Invention Grant
- Patent Title: Substituted pyrimidinones as agonists of the APJ receptor
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Application No.: US17051212Application Date: 2019-04-30
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Publication No.: US11807624B2Publication Date: 2023-11-07
- Inventor: Vatee Pattaropong , Philip Dean Ramsden
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Fenwick & West LLP
- Agent Glenn J. Foulds
- International Application: PCT/US2019/029780 2019.04.30
- International Announcement: WO2019/213006A 2019.11.07
- Date entered country: 2020-10-28
- Main IPC: C07D239/545
- IPC: C07D239/545 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/14

Abstract:
Compounds of Formula I and Formula II, pharmaceutically acceptable salts thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: Figure I and Figure II where the definitions of the variables are provided herein.
Public/Granted literature
- US20210246118A1 SUBSTITUTED PYRIMIDINONES AS AGONISTS OF THE APJ RECEPTOR Public/Granted day:2021-08-12
Information query
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