Methods, computing systems, and computer-readable media for determining flow control device settings. The method may include obtaining data representing flow rates for a plurality of flow control devices; determining total molar rates for a plurality of flows through pipe segments associated with each of the flow control devices based on the obtained data; determining initial flow control device constraints based on the total molar rates for the plurality of flow control devices; determining that one or more wellhead constraints would be violated based on the flow control device constraints; determining adjusted flow control device constraints that result in the satisfaction of one or more wellhead constraints or constraints of others of the plurality of flow control devices; determining an adjusted flow rate based on the adjusted device constraints that satisfy the wellhead and the flow control device constraints; and executing a computer-based instruction to set one or more wellhead settings and flow control device valve settings based on the adjusted flow control device constraints.