According to the embodiments of the present disclosure, there is provided a method and device of detecting fault in production, and a computer readable storage medium. The method includes: determining whether a plurality of production paths in a production line are faultless in one or more production batches, based on production record data; and determining at least one of the plurality of production paths to be faulty, at least partially based on whether the plurality of production paths are faultless in the one or more production batches.