A system and method for ejecting one or more fluids from a digital dispense device. The method includes selecting a) fixed target areas and total fluid volumes for the target areas of the substrate; b) a predetermined droplet volume for the target areas; c) calculating a required number of droplets for the target areas; d) determining a maximum number of droplets per pixel based on the target areas; e) calculating a number of droplets per pass of an ejection head over the target areas; f) modifying one or more dimension of the target areas to create modified target areas; g) selecting and centering the modified spot size target areas in the target areas; and h) depositing fluids in the modified target areas while scanning the ejection head over the modified target areas.