A glass panel support structure supports multi-glazed glass of which a circumferential edge part is bonded to a frame that frames all sides. The glass panel support structure includes a first structural sealant that bonds an indoor-side glass plate of the multi-glazed glass and the frame over an entire circumference, and a spacer provided between glass plates of the multi-glazed glass over the entire circumference. Along a first direction perpendicular to an indoor and outdoor direction of the multi-glazed glass, a position of an inner circumferential surface of the spacer is identical with a position of an inner circumferential surface of the first structural sealant or is located on outer circumferential side with respect to position of the inner circumferential surface of the first structural sealant.