Invention Grant
- Patent Title: Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization
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Application No.: US17342587Application Date: 2021-06-09
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Publication No.: US11851657B2Publication Date: 2023-12-26
- Inventor: Guangping Gao , Yi Lu , Qiang Zheng , Xun Xu , Phillip D. Zamore , Phillip Tai
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; C12N15/86 ; C12N15/11 ; A61P27/02 ; A61K9/00 ; A61K48/00
Abstract:
The disclosure relates, in some aspects, to compositions and methods for treating corneal disease (e.g., corneal neovascularization. In some embodiments, the disclosure relates to rAAV-mediated delivery of an cornea-associated transgene to a subject. In some embodiments, the rAAV transduces the corneal tissue of a subject.
Public/Granted literature
- US20210380981A1 ANTI-ANGIOGENIC MIRNA THERAPEUTICS FOR INHIBITING CORNEAL NEOVASCULARIZATION Public/Granted day:2021-12-09
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