Embodiments of the present disclosure provide a display substrate, a touch display panel and a display panel. The display substrate has a display region and a pin region on a side of the display region. The display substrate includes: a base substrate; and at least one first signal line and at least one second signal line both on a side of the base substrate and both extending to the display region from the pin region. The display substrate further includes a DC conductive structure connected to a constant DC voltage. The DC conductive structure is between the at least one first signal line and the at least one second signal line. Each of the at least one first signal line and the at least one second signal line is spaced apart from the DC conductive structure.