The present disclosure provides an array substrate and a manufacturing method thereof, a display panel and a display device. The array substrate includes: a base substrate including a display area and a border area around the display area; and a signal line and an electrode line located in the border area of the base substrate. The signal line is arranged in a same layer as a source-drain electrode layer in the display area, and the electrode line is arranged in a same layer as an anode layer in the display area. The electrode line is overlapped on a surface of the signal line away from the base substrate, overlapping surfaces of the signal line and the electrode line are two concave-convex surfaces fitted to each other.