发明授权
- 专利标题： N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE2) receptors modulators
-
申请号： US17310512申请日： 2020-02-07
-
公开(公告)号： US11872226B2公开(公告)日： 2024-01-16
- 发明人: Julio Castro Palomino Laria , Juan Camacho Gómez , Rodolfo Rodríguez Iglesias , Irene Velilla Martínez
- 申请人： MEDIBIOFARMA, S.L.
- 申请人地址： ES Navarra
- 专利权人： MEDIBIOFARMA, S.L.
- 当前专利权人： MEDIBIOFARMA, S.L.
- 当前专利权人地址： ES Navarra
- 代理机构： McKee, Voorhees & Sease, PLC
- 优先权： EP 382088 2019.02.08
- 国际申请： PCT/EP2020/053069 2020.02.07
- 国际公布： WO2020/161275A 2020.08.13
- 进入国家日期： 2021-08-06
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/195 ; A61K31/277 ; A61K31/341 ; A61K31/381 ; A61K31/415 ; A61K31/4418 ; C07C233/76 ; C07C255/59 ; C07D213/56 ; C07D231/12 ; C07D239/26 ; C07D307/58 ; C07D333/24
摘要：
The present invention relates to novel, optionally substituted, N-benzyl-2-phenoxybenzamide derivatives of formula (I), as modulators of EP4 and/or EP2 receptors of prostaglandin E2 (PGE2), to processes for their preparation, to pharmaceutical compositions comprising said compounds and to said compound for use in the treatment of pathological conditions, disorders or diseases that can improve by modulation of EP4 and/or EP2 receptors of prostaglandin E2 (PGE2) such as cancer disease, pain, inflammation, neurodegenerative diseases and kidney diseases.
公开/授权文献
信息查询
