A method of driving a display device, includes: supplying a first sensing data signal corresponding to a first grayscale, first power having a first sensing voltage, and a reference voltage to a pixel during a first sensing period; sensing a first sensing current, generated based on the first sensing voltage, from the pixel during the first sensing period; supplying a second sensing data signal corresponding to a second grayscale and different from the first sensing data signal, the first power having a second sensing voltage, and the reference voltage to the pixel during a second sensing period; sensing a second sensing current, generated based on the second sensing voltage different from the first sensing voltage, from the pixel during the second sensing period; and calculating characteristics of a driving transistor of the pixel using the first sensing current and the second sensing current.