Provided is a pair of glasses with a ventilated structure, mainly including an upper frame, a lens unit and a lower frame. The upper frame is provided with a lens groove and an inserting seat. The lens unit is arrange in the lens groove, and is provided with a plurality of air-permeable holes at the upper end of the lens unit. The lower frame is provided with an inserting section to be inserted into the inserting groove. The inserting section is provided with a positioning convex part operatively embedded in one of the adjusting holes of the adjusting unit to for a positioning. By positioning the position of the positioning convex part relative to each adjusting hole, the air-permeable holes of the lens are hidden or exposed on the upper frame.