Systems and methods are provided for in-vehicle data-driven connectivity optimization in a network of moving things. An on-board unit configured for deployment in a vehicle may obtain, during operations in an area of the network of moving things, connectivity-related data relating to coverage within the area, and generate or update, based on processing of the obtained connectivity-related data, a networking decision model. The networking decision model is configured for optimizing connectivity to the one or more access points in or associated with the network of moving things. The networking decision model may be shared with other on-board units deployed in other vehicles and/or with a Cloud-based network node in the network.